Materialise Mimics Core Mimics Medical 28: The Gold Standard for Medical 3D Image Segmentation & Engineering

Materialise Mimics Core 28 (Medical 28.x) is the flagship medical image segmentation and 3D engineering software, widely regarded as the gold standard for converting 2D medical imaging data (CT, MRI, CBCT) into precise 3D digital models . As the foundational product of the Materialise Mimics platform, it provides powerful tools for anatomical segmentation, 3D measurement, virtual surgical planning, and design preparation for 3D printing and CAD engineering.

The version 28 release (product update 2025) brings transformative improvements in speed, intelligence, and collaboration . Key highlights include a new centerline algorithm for more accurate vascular and airway modeling, AI-enabled segmentation to reduce manual workload by up to 30%, advanced alignment tools (surface registration, natural anatomical position), and enhanced Python API for workflow automation . Additionally, it now supports NIfTI and RT-DICOM formats, broadening its utility in radiotherapy and research applications.

???? Primary Users

This professional medical 3D engineering software is designed for:

• Biomedical Engineers & Clinical Researchers converting medical images (CT, MRI) into accurate 3D models for analysis and device design

• Medical Device Manufacturers designing patient-specific implants, surgical guides, and instruments using anatomical data

• Orthopedic & Craniomaxillofacial Surgeons performing virtual surgical planning and simulating complex bone corrections

• Radiologists & Imaging Specialists processing DICOM data for advanced visualization and 3D reconstruction

• Regulated Medical Device Companies seeking validated software for end-to-end personalized medicine workflows

⚡ Key Features & Capabilities

???? AI-Enabled & Automated Segmentation

• AI-Assisted Anatomy Reconstruction – Utilizes cloud-based AI algorithms (via Mimics Flow) to automatically segment healthy anatomy. Version 28 now offers algorithms for orthognathic, reconstruction, and shoulder cases, reducing segmentation time by up to 30% .

• Smart Editing Tools – Refine AI-generated masks with intuitive editing brushes, hole filling, and region growing tools .

• Multi-Planar Reconstruction (MPR) – Segment simultaneously in axial, coronal, sagittal, and 3D views .

???? Enhanced Anatomical Analysis & Alignment

????️ Virtual Surgery Planning (VSP) Tools

• Cutting & Separation – Create complex osteotomy planes, separate bone fragments, and simulate corrections .

• Collision Prevention & Positioning – New “Collision Prevention” tool helps avoid overlapping fragments during virtual reduction of fractures (e.g., mandible or pelvis) .

• 3D Measurement Library – Comprehensive tools for distance, angle, volume, and surface area analysis directly on the 3D model .

• View & Positioning Management – Easily toggle between pre-op, plan, and post-op views to share multi-stage case progress and communicate with peers .

???? Seamless Workflow Integration & Automation

• Mimics Flow Integration – Cloud-desktop hybrid platform. Users can access AI segmentation in the cloud while performing detailed editing offline on the desktop .

• Python API – Version 28 adds 15+ new operations to the Python API, allowing users to automate repetitive tasks (e.g., batch exporting, standard measurements) and integrate with the latest Python versions .

• 3-matic Integration – Seamless one-click transfer of models to 3-matic Medical for CAD design, FEA meshing, and surface wrapping .

• Data Interoperability – Supports DICOM, NIfTI, RT-DICOM, and export to major CAD, FEA, and 3D printing formats (STL, OBJ, VRML) .

???? What’s New in Version 28.x (Product Update 2025)

Version 28 represents a major update focused on accelerating the “case-to-care” pathway .

l education, simulation, and for fabricating custom medical devices and implants.